Retinal Nerve Fiber Layer Thickness (RNFLT) in Myopic & Hypermetropic Eyes in a Subset of Pakistani Population

Life and Science Pub Date : 2024-01-15 DOI:10.37185/lns.1.1.480

Sahrish Mukhtar, Nuzhat Hassan, M. Lakhani, Urooj Fatima, S. Shaheen, Iffat Raza

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Abstract

Objective: This study aimed to evaluate retinal nerve fiber layer (RNFL) thickness in healthy individuals with myopic and hypermetropic eyes, using optical coherence tomography (OCT).Study Design: A cross-sectional study. Place and Duration of Study: The study was carried out at the Department of Ophthalmology, Dr. Akil bin Abdul Qadir Institute of Ophthalmology, Karachi, Pakistan from January 2015 to June 2015.Methods: In this study, 300 eyes were included were examined using standard protocols by a single examiner. Subjects with a history of diabetic or hypertensive retinopathy, raised intraocular pressure (> 21mmHg), and previous intraocular or laser surgery were excluded from the study. The mean retinal nerve fiber layer thickness was calculated in both myopic and hypermetropic eyes. Results: The mean global retinal nerve fiber layer thickness (RNFLT) in myopic eyes was found to be 93.98 ± 8.57 μm. In hypermetropic eyes, it was found to be 101.00 ± 6.58. This variation was found to be statistically significant with p-value of 0.001.Conclusion: We concluded that individuals with myopic eyes had significantly reduced retinal nerve fiber layer thickness whereas those with hypermetropic eyes showed an insignificant increase in RNFLT compared to emmetropic eyes.How to cite this: Mukhtar S, Hassan N, Lakhani M, Fatima U, Shaheen S, Raza I. Retinal Nerve Fiber Layer Thickness (RNFLT) in Myopic & Hypermetropic Eyes in a Subset of Pakistani Population. Life and Science. 2024; 5(1): 54-60. doi: http://doi.org/10.37185/LnS.1.1.480

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巴基斯坦部分人群近视眼和高度近视眼的视网膜神经纤维层厚度 (RNFLT)

研究目的本研究旨在使用光学相干断层扫描（OCT）评估健康近视眼和高度近视眼患者的视网膜神经纤维层（RNFL）厚度：横断面研究。研究地点和时间：研究于 2015 年 1 月至 2015 年 6 月在巴基斯坦卡拉奇阿基勒-本-阿卜杜勒-卡迪尔博士眼科研究所眼科部进行：本研究共纳入 300 只眼睛，由一名检查员采用标准方案进行检查。有糖尿病或高血压视网膜病变病史、眼压升高（> 21mmHg）以及曾做过眼内手术或激光手术的受试者不在研究范围内。计算近视眼和高度屈光不正眼的平均视网膜神经纤维层厚度。结果显示近视眼的平均视网膜神经纤维层厚度（RNFLT）为 93.98 ± 8.57 μm。在高度近视眼中，平均值为 101.00 ± 6.58。这一差异具有统计学意义，P 值为 0.001：结论：我们得出结论，近视眼患者的视网膜神经纤维层厚度明显减少，而与弱视眼相比，高度近视眼患者的视网膜神经纤维层厚度增加不明显：Mukhtar S, Hassan N, Lakhani M, Fatima U, Shaheen S, Raza I. 巴基斯坦人群近视眼和远视眼的视网膜神经纤维层厚度（RNFLT）。生命与科学2024; 5(1):54-60. DOI: http://doi.org/10.37185/LnS.1.1.480

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