Early diagnosis and treatment strategies for pediatric growth hormone deficiency

Abstract

Over the last century, adult height has shown a marked increase, largely attributed to advancements in nutrition and healthcare. Monitoring child growth is crucial for the early identification of growth-related disorders. One such condition is the underperformance of the pituitary gland, which can lead to a deficiency in growth hormone, manifesting as short stature. Therapeutic interventions, such as growth hormone therapy and low-dose androgen therapy, have proven effective. These treatments utilize synthetic hormones to foster normal growth. Prompt and accurate diagnosis, coupled with precise treatment, is critical to empower individuals to reach their maximum growth potential and alleviate associated health concerns. Future research should aim to deepen our understanding of the interplay between pituitary cells, uncover additional genetic factors contributing to short stature, and enhance growth hormone replacement therapies. Such progress will significantly bolster the diagnostic and therapeutic strategies for children with growth impairments.