Odille Mejia-Mejia, Andres Bravo-Gonzalez, Monica Sanchez-Avila, Youley Tjendra, Rodrigo Santoscoy, Katherine Drews-Elger, Yiqin Zuo, Camilo Arias-Abad, Carmen Gomez, Monica Garcia-Buitrago, Mehrdad Nadji, Merce Jorda, Jaylou M. Velez-Torres, Roberto Ruiz-Cordero
{"title":"Atypia of Undetermined Significance and ThyroSeq v3 Positive Call Rates as Quality Control Metrics for Cytology Laboratory Performance","authors":"Odille Mejia-Mejia, Andres Bravo-Gonzalez, Monica Sanchez-Avila, Youley Tjendra, Rodrigo Santoscoy, Katherine Drews-Elger, Yiqin Zuo, Camilo Arias-Abad, Carmen Gomez, Monica Garcia-Buitrago, Mehrdad Nadji, Merce Jorda, Jaylou M. Velez-Torres, Roberto Ruiz-Cordero","doi":"10.1101/2024.01.24.24301631","DOIUrl":null,"url":null,"abstract":"<strong>Background</strong> The Bethesda system (TBS) for reporting thyroid cytopathology recommends an “atypia of undetermined significance (AUS)” rate of 10%. Recent data suggest that this category might be overused when the rate of cases with molecular positive results is low. As a quality metric, we calculated the AUS and positive call rates for our cytology lab and each cytopathologist.","PeriodicalId":501528,"journal":{"name":"medRxiv - Pathology","volume":"10 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Pathology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.01.24.24301631","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background The Bethesda system (TBS) for reporting thyroid cytopathology recommends an “atypia of undetermined significance (AUS)” rate of 10%. Recent data suggest that this category might be overused when the rate of cases with molecular positive results is low. As a quality metric, we calculated the AUS and positive call rates for our cytology lab and each cytopathologist.