Atypia of Undetermined Significance and ThyroSeq v3 Positive Call Rates as Quality Control Metrics for Cytology Laboratory Performance

Odille Mejia-Mejia, Andres Bravo-Gonzalez, Monica Sanchez-Avila, Youley Tjendra, Rodrigo Santoscoy, Katherine Drews-Elger, Yiqin Zuo, Camilo Arias-Abad, Carmen Gomez, Monica Garcia-Buitrago, Mehrdad Nadji, Merce Jorda, Jaylou M. Velez-Torres, Roberto Ruiz-Cordero
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Abstract

Background The Bethesda system (TBS) for reporting thyroid cytopathology recommends an “atypia of undetermined significance (AUS)” rate of 10%. Recent data suggest that this category might be overused when the rate of cases with molecular positive results is low. As a quality metric, we calculated the AUS and positive call rates for our cytology lab and each cytopathologist.
意义未定的不典型性和 ThyroSeq v3 阳性调用率作为细胞学实验室绩效的质量控制指标
背景 用于报告甲状腺细胞病理学的贝塞斯达系统(TBS)建议 "意义未定的不典型性(AUS)"率为 10%。最近的数据表明,当分子检测结果呈阳性的病例比例较低时,这一类别可能会被过度使用。作为一项质量指标,我们计算了细胞学实验室和每位细胞病理学家的 AUS 和阳性呼叫率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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