Floris Vanommeslaeghe MD, PhD , Wim Van Biesen MD, PhD , Karlien François MD, PhD
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引用次数: 0
Abstract
Maintaining patency of the extracorporeal hemodialysis (HD) circuit is a prerequisite to perform HD. Unfractionated heparin and low-molecular-weight heparins are the most used anticoagulants in maintenance HD, but their administration comes with a major trade-off of bleeding complications. This narrative review article discusses technical factors impacting on HD circuit patency, such as tubings, dialyzer membranes, priming practices, and treatment settings. Strategies for monitoring extracorporeal circuit clotting during and after treatment are also reviewed, as these are essential tools for optimizing anticoagulation.
保持体外血液透析(HD)回路的通畅是进行 HD 的先决条件。非分叶肝素和低分子量肝素是维持性血液透析中最常用的抗凝剂,但在使用这些药物的同时也会出现出血并发症。这篇叙述性综述文章讨论了影响血液透析回路通畅性的技术因素,如管道、透析膜、引流方法和治疗设置。文章还回顾了治疗期间和治疗后监测体外循环凝血的策略,因为这些都是优化抗凝的重要工具。
期刊介绍:
Seminars in Nephrology is a timely source for the publication of new concepts and research findings relevant to the clinical practice of nephrology. Each issue is an organized compendium of practical information that serves as a lasting reference for nephrologists, internists and physicians in training.