Meme Kanserine Bağlı Beyin Metastazlarında Difüzyon Ağırlıklı Görüntüleme ile Histopatolojik Tip Arasında Bir İlişki Var mı?

Sağlık Bilimlerinde Değer Pub Date : 2024-01-16 DOI:10.33631/sabd.1346821

Şeyhmus Kavak, Nazan Çi̇ledağ

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Abstract

Aim: The aim of this study is to evaluate the relationship between diffusion-weighted imaging (DWI) properties and apparent diffusion coefficient (ADC) values of metastases with the histological type of breast cancer in patients with breast cancer-related brain metastasis. Material and Methods: Between May 2008 - April 2011, 57 female patients who had been previously diagnosed with breast cancer in the radiology clinic were included in the study. Cases with invasive ductal carcinoma were considered group 1 (46 patients, 89 lesions) and cases with invasive lobular, comedo carcinoma and papillary cribriform carcinoma were considered group 2 ( 11 patients, 25 lesions). ADC values in both groups were compared by statistical analysis methods. Results: In group 1; 37 lesions (41.57%) and in group 2; 13 lesions (52%) included cystic component. In the group of invasive ductal carcinoma 48 lesions (53.92%) and 18 lesions (72%) of second group included peritumoral edema. The mean ADC value of the solid component of metastases (group1: 1.105x10-3mm2/ s, group2: 1.099x10-3mm2/ s) was higher than the average ADC value of normal brain parenchyma (group1: 0.790x10-3mm2/s, group2: 0.801x10-3mm2/s), and was statistically significant (p

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扩散加权成像与乳腺癌脑转移瘤的组织病理学类型有关系吗？

目的：本研究旨在评估乳腺癌相关脑转移患者转移灶的弥散加权成像（DWI）特性和表观弥散系数（ADC）值与乳腺癌组织学类型之间的关系。材料与方法：2008年5月至2011年4月期间，57名曾在放射科门诊确诊为乳腺癌的女性患者被纳入研究。浸润性导管癌病例被视为第一组（46 名患者，89 个病灶），浸润性小叶癌、comedo 癌和乳头状楔形癌病例被视为第二组（11 名患者，25 个病灶）。两组的 ADC 值通过统计分析方法进行比较。结果：第 1 组有 37 个病灶（41.57%），第 2 组有 13 个病灶（52%）包含囊性成分。浸润性导管癌组 48 个病灶（53.92%）和第二组 18 个病灶（72%）包括瘤周水肿。转移瘤实体成分的平均 ADC 值（第一组：1.105x10-3mm2/s，第二组：1.099x10-3mm2/s）高于正常脑实质的平均 ADC 值（第一组：0.790x10-3mm2/s，第二组：0.801x10-3mm2/s），且有统计学意义（P＜0.05）。

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