A view on vitamin D: a pleiotropic factor?

IF 3.7 3区医学 Q2 CHEMISTRY, MEDICINAL

Chemical Research in Toxicology Pub Date : 2024-01-22 DOI:10.1038/s41574-023-00942-0

Andrea Giustina, Marise Lazaretti-Castro, Adrian R. Martineau, Rebecca S. Mason, Clifford J. Rosen, Inez Schoenmakers

引用次数: 0

Abstract

Vitamin D is precursor of the steroid hormone calcitriol and has important functions throughout the body, including increasing intestinal absorption of calcium, magnesium and phosphate. Vitamin D deficiency has been linked with a range of disorders, including several bone diseases. However, large trials of vitamin D supplementation have produced mixed results. Here, experts from around the world discuss several key questions in the vitamin D research and clinical fields.

查看原文本刊更多论文

对维生素 D 的看法：多效因子？

维生素 D 是类固醇激素钙三醇的前体，在全身具有重要功能，包括增加肠道对钙、镁和磷酸盐的吸收。维生素 D 缺乏与一系列疾病有关，包括多种骨病。然而，补充维生素 D 的大型试验结果喜忧参半。在此，来自世界各地的专家将讨论维生素 D 研究和临床领域的几个关键问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Chemical Research in Toxicology 医学-毒理学

CiteScore

7.90

自引率

7.30%

发文量

215

审稿时长

3.5 months

期刊介绍： Chemical Research in Toxicology publishes Articles, Rapid Reports, Chemical Profiles, Reviews, Perspectives, Letters to the Editor, and ToxWatch on a wide range of topics in Toxicology that inform a chemical and molecular understanding and capacity to predict biological outcomes on the basis of structures and processes. The overarching goal of activities reported in the Journal are to provide knowledge and innovative approaches needed to promote intelligent solutions for human safety and ecosystem preservation. The journal emphasizes insight concerning mechanisms of toxicity over phenomenological observations. It upholds rigorous chemical, physical and mathematical standards for characterization and application of modern techniques.