Sebastian Lobentanzer, Pablo Rodriguez-Mier, Stefan Bauer, Julio Saez-Rodriguez
{"title":"Molecular causality in the advent of foundation models","authors":"Sebastian Lobentanzer, Pablo Rodriguez-Mier, Stefan Bauer, Julio Saez-Rodriguez","doi":"arxiv-2401.09558","DOIUrl":null,"url":null,"abstract":"Correlation is not causation. As simple as this widely agreed-upon statement\nmay seem, scientifically defining causality and using it to drive our modern\nbiomedical research is immensely challenging. In this perspective, we attempt\nto synergise the partly disparate fields of systems biology, causal reasoning,\nand machine learning, to inform future approaches in the field of systems\nbiology and molecular networks.","PeriodicalId":501325,"journal":{"name":"arXiv - QuanBio - Molecular Networks","volume":"36 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"arXiv - QuanBio - Molecular Networks","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/arxiv-2401.09558","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Correlation is not causation. As simple as this widely agreed-upon statement
may seem, scientifically defining causality and using it to drive our modern
biomedical research is immensely challenging. In this perspective, we attempt
to synergise the partly disparate fields of systems biology, causal reasoning,
and machine learning, to inform future approaches in the field of systems
biology and molecular networks.