Parametric modal regression with error in covariates

IF 1.3 3区 生物学 Q4 MATHEMATICAL & COMPUTATIONAL BIOLOGY
Qingyang Liu, Xianzheng Huang
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引用次数: 0

Abstract

An inference procedure is proposed to provide consistent estimators of parameters in a modal regression model with a covariate prone to measurement error. A score-based diagnostic tool exploiting parametric bootstrap is developed to assess adequacy of parametric assumptions imposed on the regression model. The proposed estimation method and diagnostic tool are applied to synthetic data generated from simulation experiments and data from real-world applications to demonstrate their implementation and performance. These empirical examples illustrate the importance of adequately accounting for measurement error in the error-prone covariate when inferring the association between a response and covariates based on a modal regression model that is especially suitable for skewed and heavy-tailed response data.

带有协变量误差的参数模态回归
提出了一种推理程序,以提供带有易出现测量误差的协变量的模态回归模型中参数的一致估计值。利用参数自举法开发了一种基于分数的诊断工具,用于评估对回归模型施加的参数假设是否充分。所提出的估计方法和诊断工具被应用于模拟实验生成的合成数据和实际应用中的数据,以展示它们的实施和性能。这些实证例子说明,在根据模态回归模型推断响应与协变量之间的关联时,充分考虑易出错协变量的测量误差非常重要,而模态回归模型尤其适用于偏斜和重尾响应数据。
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来源期刊
Biometrical Journal
Biometrical Journal 生物-数学与计算生物学
CiteScore
3.20
自引率
5.90%
发文量
119
审稿时长
6-12 weeks
期刊介绍: Biometrical Journal publishes papers on statistical methods and their applications in life sciences including medicine, environmental sciences and agriculture. Methodological developments should be motivated by an interesting and relevant problem from these areas. Ideally the manuscript should include a description of the problem and a section detailing the application of the new methodology to the problem. Case studies, review articles and letters to the editors are also welcome. Papers containing only extensive mathematical theory are not suitable for publication in Biometrical Journal.
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