Comparison of clinical outcomes in patients with mixed angina and pure vasospastic angina.

IF 1.5 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Coronary artery disease Pub Date : 2024-06-01 Epub Date: 2024-01-22 DOI:10.1097/MCA.0000000000001330

Zhao Yan Song, Moo Hyun Kim, Kwang Min Lee

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引用次数: 0

Abstract

Objective: This study investigated differences in clinical outcomes between mixed angina (MA) and pure vasospastic angina (PVA).

Methods: A total of 524 vasospastic angina patients who did or did not have >50% coronary artery stenosis from January 2005 to January 2021 were divided into two groups (Group 1: PVA, N = 399; Group 2: MA, N = 125) and then three groups [Group 1: PVA, N = 399; Group 2: MA without percutaneous coronary intervention (PCI), N = 67; Group 3: MA with PCI, N = 58] for assessment. We recorded the incidence of major adverse cardiac and cerebrovascular events (MACCE: the composite of death, myocardial infarction, nonfatal stroke or rehospitalization) during 3-year clinical follow-up.

Results: Compared to the PVA group, there were significant differences in MACCE (20.8% vs. 11.8%, P = 0.011) and rehospitalization (20.0% vs. 9.8%, P = 0.002) in the MA group. Kaplan-Meier analysis showed that patients in the MA with PCI group had the highest cumulative incidence rate of MACCE during the 3-year follow-up (log-rank P < 0.001).

Conclusion: Compared with the PVA patients, MA patients had significantly worse clinical outcomes during long-term follow-up.

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混合型心绞痛和单纯血管痉挛性心绞痛患者临床疗效的比较。

目的：本研究调查了混合型心绞痛（MA）和单纯性血管痉挛性心绞痛（PVA）的临床结果差异：本研究探讨了混合型心绞痛（MA）与单纯血管痉挛性心绞痛（PVA）临床疗效的差异：2005年1月至2021年1月期间，524名冠状动脉狭窄>50%的血管痉挛性心绞痛患者被分为两组（第1组：PVA，N = 399；第2组：MA，N = 125），然后分为三组[第1组：PVA，N = 399；第2组：MA，无经皮冠状动脉介入治疗（PCI），N = 67；第3组：MA，无经皮冠状动脉介入治疗（PCI），N = 67]：然后分三组进行评估[组 1：PVA，399 人；组 2：MA，无经皮冠状动脉介入治疗 (PCI)，67 人；组 3：MA，PCI，58 人]。我们记录了3年临床随访期间主要心脑血管不良事件（MACCE：死亡、心肌梗死、非致命性卒中或再住院的综合）的发生率：与 PVA 组相比，MA 组的 MACCE（20.8% 对 11.8%，P=0.011）和再住院率（20.0% 对 9.8%，P=0.002）有显著差异。Kaplan-Meier分析显示，MA与PCI组患者在3年随访期间的MACCE累积发生率最高（log-rank P 结论）：与 PVA 患者相比，MA 患者在长期随访期间的临床预后明显较差。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Coronary artery disease 医学-外周血管病

CiteScore

2.50

自引率

0.00%

发文量

190

审稿时长

6-12 weeks

期刊介绍： Coronary Artery Disease welcomes reports of original research with a clinical emphasis, including observational studies, clinical trials, translational research, novel imaging, pharmacology and interventional approaches as well as advances in laboratory research that contribute to the understanding of coronary artery disease. Each issue of Coronary Artery Disease is divided into four areas of focus: Original Research articles, Review in Depth articles by leading experts in the field, Editorials and Images in Coronary Artery Disease. The Editorials will comment on selected original research published in each issue of Coronary Artery Disease, as well as highlight controversies in coronary artery disease understanding and management. Submitted artcles undergo a preliminary review by the editor. Some articles may be returned to authors without further consideration. Those being considered for publication will undergo further assessment and peer-review by the editors and those invited to do so from a reviewer pool.