The renin angiotensin aldosterone system.

IF 2.9 4区医学 Q2 PHYSIOLOGY

Pflugers Archiv : European journal of physiology Pub Date : 2024-05-01 Epub Date: 2024-01-17 DOI:10.1007/s00424-024-02908-1

Hannah Triebel, Hayo Castrop

引用次数: 0

Abstract

In this review, we will cover (i) the proteolytic cascade of the RAAS, (ii) its regulation by multiple feedback-controlled parameters, and (iii) the major effects of the RAAS. For the effects of the RAAS, we focus on the role of the RAAS in the regulation of volume homeostasis and vascular tone, as major determinants of arterial blood pressure.

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肾素血管紧张素醛固酮系统。

在这篇综述中，我们将介绍：(i) RAAS 的蛋白水解级联；(ii) RAAS 受多种反馈控制参数的调节；(iii) RAAS 的主要作用。关于 RAAS 的作用，我们将重点讨论 RAAS 在调节血容量平衡和血管张力方面的作用，因为它们是动脉血压的主要决定因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pflugers Archiv : European journal of physiology 医学-生理学

CiteScore

8.80

自引率

2.20%

发文量

121

审稿时长

4-8 weeks

期刊介绍： Pflügers Archiv European Journal of Physiology publishes those results of original research that are seen as advancing the physiological sciences, especially those providing mechanistic insights into physiological functions at the molecular and cellular level, and clearly conveying a physiological message. Submissions are encouraged that deal with the evaluation of molecular and cellular mechanisms of disease, ideally resulting in translational research. Purely descriptive papers covering applied physiology or clinical papers will be excluded. Papers on methodological topics will be considered if they contribute to the development of novel tools for further investigation of (patho)physiological mechanisms.