Influence of colorectal anastomotic leakage on time before the loop stoma closing

A. A. Balkarov, M. Alekseev, E. G. Rybakov, Y. Shelygin
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Abstract

Background. Important task is determining the long-term consequences of colorectal anastomotic leakage. Leakage with clinical manifestations leads to a higher frequency of local recurrences of rectal cancer and increases the severity of manifestations of low anterior resection syndrome. How does the leakage of colorectal anastomosis affect the period before the closure of loop stoma?Aim. To determine the influence of anastomotic leakage on the term before closing the ileostomy.Methods. In this retrospective incomparable study were included 618 patients with rectal cancer who had been underwent anterior or low anterior resection with formation colorectal anastomosis and loop stoma.Results. Colorectal anastomotic leakage was detected in 86 from 618 patients (13.9 %). The loop stoma was closed in 513 from 618 (83 %) patients. The time to the preventive stoma closure in patients with anastomotic leakage was significantly higher than in patients without anastomotic leakage, p = 0.001. Reconstructive surgery in patients without anastomotic leakage was performed in 9 months after anterior resection. The median time before the stoma closure of patients with X – ray anastomosis leakage was 11 months, with clinical leakage – 17 months, p <0.001.Conclusion. Colorectal anastomotic leakage statistically increases the term before ileostomy closure.
大肠吻合口漏对环形造口关闭前时间的影响
背景。确定结肠直肠吻合口漏的长期后果是一项重要任务。有临床表现的渗漏会导致直肠癌局部复发的频率升高,并增加低位前切除综合征表现的严重性。结肠直肠吻合口渗漏对环形造口关闭前的影响如何?确定吻合口渗漏对回肠造口关闭前的影响。在这项不可比较的回顾性研究中,共纳入了618例直肠癌患者,他们都接受了前路或低前路切除术,并形成了结直肠吻合口和环形造口。618 例患者中有 86 例(13.9%)发现结肠直肠吻合口漏。618 例患者中有 513 例(83%)关闭了环形造口。吻合口漏患者预防性造口关闭的时间明显高于无吻合口漏患者,P = 0.001。无吻合口漏患者的重建手术是在前端切除术后 9 个月进行的。X 射线吻合口渗漏患者造口关闭前的中位时间为 11 个月,临床渗漏患者为 17 个月,P <0.001。结肠直肠吻合口漏会在统计学上增加回肠造口关闭前的时间。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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