Aakash Ramanishankar, Ankul Singh S, Rukaiah F Begum, Narayanan Jayasankar, Afreen Nayeem, B. Prajapati, Shanmugasundaram Nirenjen
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引用次数: 0
Abstract
Aim: Photobiomodulation involves the use of low-level light therapy or near-infrared light therapy found to be useful in the treatment of a wide range of neurological diseases. Objective: The aim is to review the mechanism and clinical applications of photobiomodulation therapy (PBMT) in managing Alzheimer's disease. Methods: To ensure that the consensus statement accurately reflects both the experts' viewpoint and the most recent developments in the field, the expert opinions were recorded and thoroughly reviewed. Results: PBMT elicits reduction of beta-amyloid plaque, restoration of mitochondrial function, anti-inflammatory and antioxidant properties with a stimulation in ATP synthesis. Conclusion: The PBMT could be helpful in patients non-responsive to traditional pharmacological therapy providing significant aid in the management of Alzheimer's disease when introduced into the medical field.
目的:光生物调节涉及使用低强度光疗法或近红外线光疗法,这些疗法被认为可用于治疗多种神经系统疾病。目的旨在回顾光生物调控疗法(PBMT)治疗阿尔茨海默病的机制和临床应用。方法:为确保共识声明准确反映专家观点和该领域的最新进展,对专家意见进行了记录和全面审查。结果:PBMTPBMT 可减少β-淀粉样蛋白斑块、恢复线粒体功能、抗炎和抗氧化并促进 ATP 合成。结论:对传统药物疗法无反应的患者可以使用 PBMT,该疗法一旦被引入医疗领域,将为阿尔茨海默病的治疗提供重要帮助。
期刊介绍:
Future Science OA is an online, open access, peer-reviewed title from the Future Science Group. The journal covers research and discussion related to advances in biotechnology, medicine and health. The journal embraces the importance of publishing all good-quality research with the potential to further the progress of research in these fields. All original research articles will be considered that are within the journal''s scope, and have been conducted with scientific rigour and research integrity. The journal also features review articles, editorials and perspectives, providing readers with a leading source of commentary and analysis. Submissions of the following article types will be considered: -Research articles -Preliminary communications -Short communications -Methodologies -Trial design articles -Trial results (including early-phase and negative studies) -Reviews -Perspectives -Commentaries