Kikuchi fujimoto disease in a young male post-COVID -19 vaccination

Sekar Manjani, Jackson Bose, Jamunarani Srirangaramasamy, Khowsalya Subrajaa Karupasamy
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Abstract

Kikuchi disease (Kikuchi-Fujimoto disease) is one of the rarest forms of lymphadenopathy. It is also known as necrotizing lymphadenitis. The patients usually present with fever and lymphadenopathy. Here is a case of Kikuchi-Fujimoto disease presented with fever and cervical lymphadenopathy. Radiological imaging revealed matted lymph nodes. Fine needle aspiration of the lymph node revealed granulomatous inflammation. Acid Fast stain was negative and further investigations ruled out tuberculosis. A histopathological biopsy of the lymph node confirmed the diagnosis of Kikuchi-Fujimoto disease. The patient was treated with medications and the patient's condition improved in follow-up. Tuberculosis must be ruled out in such conditions as the symptoms and radiological and FNAC findings mimicking tuberculosis. The diagnosis of Kikuchi-Fujimoto disease is made by histopathology and confirmed by immunohistochemistry.
一名接种 COVID -19 疫苗后的年轻男性患上菊池藤本氏病
菊池病(菊池-藤本病)是淋巴腺病中最罕见的一种。它也被称为坏死性淋巴结炎。患者通常表现为发热和淋巴结病。这是一例以发热和颈淋巴结病为主要表现的菊地-藤本氏病。影像学检查发现淋巴结呈哑铃状。淋巴结细针穿刺显示肉芽肿性炎症。酸性快速染色呈阴性,进一步检查排除了结核病的可能。淋巴结的组织病理活检证实了菊地-藤本氏病的诊断。患者接受了药物治疗,随访期间病情有所好转。在症状、放射学和 FNAC 检查结果类似结核病的情况下,必须排除结核病。菊地-藤本氏病的诊断是通过组织病理学做出的,并通过免疫组化进行确诊。
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