MCR-based heteroannulations: A direct access to fused tetrazolo piperazinones and 1,4-diazepanones

Abstract

Exploiting the chemistry of bifunctional isocyanides, straightforward, rapid and scalable Ugi-tetrazole-based MCR heteroannulations are described. Our synthetic approach provides a series of diverse fused tetrazolo piperazinones and 1,4-diazepanones in just one step.