Human Mycobiota and Its Role in Cancer Progression, Diagnostics and Therapeutics: A Link Lesser-Known.

IF 1.8 4区 医学 Q3 ONCOLOGY
Cancer Investigation Pub Date : 2024-01-01 Epub Date: 2024-01-07 DOI:10.1080/07357907.2024.2301733
Souvik Roy, Dhrisaj Ray, Ishani Laha, Lopamudra Choudhury
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引用次数: 0

Abstract

Although not as well studied as the bacterial component of the human microbiota, the commensal fungi or mycobiota play important roles in maintaining our health by augmenting our immune system. This mycobiota is also associated with various fatal diseases like opportunistic mycoses, and even cancer, with different cancers having respective type-specific mycobiota. The different fungal species which comprise these different intratumoral mycobiota play important roles in cancer progression. The aim of this review paper is to decipher the association between mycobiota and cancer, and shed light on new avenues in cancer diagnosis, and the development of new anti-cancer therapeutics.

人类霉菌生物群及其在癌症进展、诊断和治疗中的作用:鲜为人知的联系
共生真菌或真菌生物群虽然不像人类微生物群中的细菌成分那样得到深入研究,但它们通过增强我们的免疫系统,在维护我们的健康方面发挥着重要作用。真菌生物群还与各种致命疾病有关,如机会性真菌病,甚至癌症,不同的癌症有各自特定类型的真菌生物群。组成这些不同瘤内真菌生物群的不同真菌种类在癌症进展中发挥着重要作用。这篇综述旨在解读真菌生物群与癌症之间的关系,为癌症诊断和开发新的抗癌疗法提供新的思路。
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来源期刊
Cancer Investigation
Cancer Investigation 医学-肿瘤学
CiteScore
3.80
自引率
4.20%
发文量
71
审稿时长
8.5 months
期刊介绍: Cancer Investigation is one of the most highly regarded and recognized journals in the field of basic and clinical oncology. It is designed to give physicians a comprehensive resource on the current state of progress in the cancer field as well as a broad background of reliable information necessary for effective decision making. In addition to presenting original papers of fundamental significance, it also publishes reviews, essays, specialized presentations of controversies, considerations of new technologies and their applications to specific laboratory problems, discussions of public issues, miniseries on major topics, new and experimental drugs and therapies, and an innovative letters to the editor section. One of the unique features of the journal is its departmentalized editorial sections reporting on more than 30 subject categories covering the broad spectrum of specialized areas that together comprise the field of oncology. Edited by leading physicians and research scientists, these sections make Cancer Investigation the prime resource for clinicians seeking to make sense of the sometimes-overwhelming amount of information available throughout the field. In addition to its peer-reviewed clinical research, the journal also features translational studies that bridge the gap between the laboratory and the clinic.
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