Low-Grade Gliomas Genetics In The Pediatric Patients Group, A Review On Some Important Notes

Abstract

Low-grade gliomas are among the most common CNS tumors in the pediatric patients group. From the genetics, histopathology, treatment strategies, distribution and molecular points of view, these tumors are different from ones which can be seen in the adult patients group. From the histological point of view, low-grade gliomas in the pediatric patients group encompass tumors of oligodendroglial, astrocytic and mixed glial-neuronal histology. Transforming into malignancy would usually not occur in most of these tumors. Understanding the genetics of these tumors is of importance in learning their behaviors. This brief review tries to point to some important notes about the genetics of the low-grade gliomas in the pediatric patients group.