Screening Preeclampsia and the Role of Low Dose Aspirin for the Prevention of Preeclampsia

Open Access Macedonian Journal of Medical Sciences Pub Date : 2023-07-21 DOI:10.3889/oamjms.2023.11214

Wayan Artana Putra

引用次数: 0

Abstract

Preeclampsia is one of the leading causes of maternal morbidity and can affect fetal conditions such as inhibition of intrauterine growth, premature labor, placental abruption, fetal distress, and, worst of all, intrauterine fetal death. In contrast to the decreasing incidence of pregnancies with infection, preeclampsia did not decrease significantly during the past two decades. Prevention of preeclampsia is an effort that is currently being intensively carried out to reduce morbidity and mortality of pregnant women. Prophylactic administration of low-dose aspirin (81 mg/day) is recommended in women with a high risk of preeclampsia. It should be started between 12 weeks of gestation to 18 weeks (optimal before 16 weeks). Aspirin has been shown to be safe for the mother and the fetus during pregnancy. Treatment with aspirin also did not increase the risk of developing congenital malformations and had no adverse effect on fetal development or bleeding complications during the neonatal period.

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筛查子痫前期和低剂量阿司匹林在预防子痫前期中的作用

子痫前期是孕产妇发病的主要原因之一，并可影响胎儿状况，如抑制宫内生长、早产、胎盘早剥、胎儿窘迫，最严重的是胎儿宫内死亡。与感染性妊娠发病率下降形成鲜明对比的是，子痫前期在过去二十年中并没有显著下降。为了降低孕妇的发病率和死亡率，目前正在大力开展子痫前期的预防工作。建议先兆子痫高危孕妇预防性服用低剂量阿司匹林（81 毫克/天）。应在妊娠 12 周至 18 周之间开始服用（16 周之前服用最佳）。阿司匹林已被证明对孕期的母亲和胎儿是安全的。使用阿司匹林也不会增加先天性畸形的风险，对胎儿发育和新生儿期出血并发症也没有不良影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Open Access Macedonian Journal of Medical Sciences Medicine-Medicine (all)

自引率

0.00%

发文量

1225

期刊介绍： Open Access Macedonian Journal of Medical Sciences (OAMJMS) [formerly known as Macedonian Journal of Medical Sciences] is a top-tier open access medical science journal published by the ID Design 2012/DOOEL Skopje, Rajko Zhinzifov No 48, 1000 Skopje, Republic of Macedonia. OAMJMS is an international, modern, general medical journal covering all areas in the medical sciences, from basic studies to large clinical trials and cost-effectiveness analyses. We publish mostly human studies that substantially enhance our understanding of disease epidemiology, etiology, and physiology; the development of prognostic and diagnostic technologies; trials that test the efficacy of specific interventions and those that compare different treatments; and systematic reviews. We aim to promote translation of basic research into clinical investigation, and of clinical evidence into practice. We publish occasional studies in animal models when they report outstanding research findings that are highly clinically relevant. Our audience is the international medical community as well as educators, policy makers, patient advocacy groups, and interested members of the public around the world. OAMJMS is published quarterly online version. The Open Access Macedonian Journal of Medical Sciences (OAMJMS) publishes Medical Informatics, Basic Science, Clinical Science, Case Report, Brief Communication, Public Health, Public Policy, and Review Article from all fields of medicine and related fields. This journal also publishes, continuously or occasionally, the bibliographies of the members of the Society, medical history, medical publications, thesis abstracts, book reviews, reports on meetings, information on future meetings, important events and dates, and various headings which contribute to the development of the corresponding scientific field.