Y. Shatokhin, I. Snezhko, E. V. Ryabikina, E. V. Degtereva
{"title":"DRUG NEURO INFLUENCES IN ONCOHEMATOLOGY","authors":"Y. Shatokhin, I. Snezhko, E. V. Ryabikina, E. V. Degtereva","doi":"10.61788/njn.v1i23.01","DOIUrl":null,"url":null,"abstract":"Modern drugs and schemes based on them, used in oncohematology, cause a high risk of developing many variants of neurological complications, including cytostatic-induced neurotoxicity of various origins, one of the severe complications of chemoradiotherapy. These side effects occur not only immediately after the administration of chemotherapy drugs, but also delayed, and therefore concern not only hematologists, oncologists, but also neurologists, therapists, general practitioners who carry out subsequent outpatient monitoring of patients. Reducing the clinical manifestations of these complications leads not only to an improvement in the quality of life of patients, but also to an increase in their survival. Knowledge of algorithms for early diagnosis of damage to the peripheral and central nervous system and the possibilities of using drug therapy to minimize their manifestations are necessary in the work of internists.","PeriodicalId":18831,"journal":{"name":"NATIONAL JOURNAL OF NEUROLOGY","volume":"48 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"NATIONAL JOURNAL OF NEUROLOGY","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.61788/njn.v1i23.01","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Modern drugs and schemes based on them, used in oncohematology, cause a high risk of developing many variants of neurological complications, including cytostatic-induced neurotoxicity of various origins, one of the severe complications of chemoradiotherapy. These side effects occur not only immediately after the administration of chemotherapy drugs, but also delayed, and therefore concern not only hematologists, oncologists, but also neurologists, therapists, general practitioners who carry out subsequent outpatient monitoring of patients. Reducing the clinical manifestations of these complications leads not only to an improvement in the quality of life of patients, but also to an increase in their survival. Knowledge of algorithms for early diagnosis of damage to the peripheral and central nervous system and the possibilities of using drug therapy to minimize their manifestations are necessary in the work of internists.