Diagnostic Test of Blood Eosinophil Level as a Marker of Ascaris lumbricoides Infection

Indonesian Journal of Tropical and Infectious Disease Pub Date : 2023-08-08 DOI:10.20473/ijtid.v11i2.46603

Said Munazar Rahmat, Merina Panggabean, Aman Agustinus Depari, Teuku Romi, Imansyah Putra, Dhiatama Endalif

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Abstract

A. lumbricoides infection is one from 17 neglected tropical diseases in Indonesia. But, Infection of A. lumbricoides in Indonesia often undiagnosed. This is because stool examination with Kato-Katz’s method still rarely done. So it needs something alternative examination that more practical and can be routinely carried out. This study was a diagnostic test for blood eosinofil levels in diagnosing A. lumbricoides infection. This research was conducted at a hospital in Medan. This study involved 63 children who had their parents approval. Children stool were examined by Kato-Katz method as a gold standard and blood eosinofil levels was examined as an index in this study. The results showed sensitivity level of eosinofil is 25% and specificity 96,08%, positive predictive value 60%, negative predictive value 84%, positive likelihood ratio 6,38% and negative likelihood ratio 0,78%. The conclusion is elevated blood eosinofil levels cannot be used as an alternative test Kato-Katz in diagnosing Infection of A. lumbricoides.

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作为蛔虫感染标志物的血液嗜酸性粒细胞水平诊断测试

瘤蛔虫感染是印度尼西亚17种被忽视的热带疾病之一。但是，印尼的蛔虫感染常常得不到诊断。这是因为使用卡托-卡茨（Kato-Katz）方法进行粪便检查的情况仍然很少。因此，需要一种更实用且可常规进行的替代检查方法。本研究是一项用于诊断蛔虫感染的血液伊红水平诊断测试。这项研究在棉兰的一家医院进行。这项研究涉及 63 名儿童，他们都得到了家长的同意。儿童粪便采用卡托-卡茨法（Kato-Katz method）作为金标准进行检测，血液中的埃希氏菌（eosinofil）水平则作为本研究的一项指标进行检测。结果显示，埃希诺菲尔的灵敏度为 25%，特异度为 96.08%，阳性预测值为 60%，阴性预测值为 84%，阳性似然比为 6.38%，阴性似然比为 0.78%。结论是血液中的埃索菲水平升高不能作为卡托-卡茨（Kato-Katz）诊断疟原虫感染的替代检测方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indonesian Journal of Tropical and Infectious Disease

自引率

0.00%

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审稿时长

12 weeks