Assessment Of Predictive Value Of Serum Uric Acid Levels For Low Birth Weight In Pre-Eclampsia

Journal of Rawalpindi Medical College Pub Date : 2023-09-26 DOI:10.37939/jrmc.v27i3.2262

Sadaf Asma, S. Muntaha, Amerzish Liaqat, Farhan Hassan, Sara Hayat, Rafiq Ahmed

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Abstract

OBJECTIVE: To assess the diagnostic accuracy of raised serum uric acid level in females with pre-eclampsia, in predicting low birth weight. SUBJESTS & METHODS: Cross sectional study carried out at Gynecology Department, FGSH Poly Clinic, Islamabad & duration of study was 6 months from July 21, 2021 to Jan 20, 2022. A total of 225 Preeclampsia pregnant female were clinically examined and included in the study. Blood sample were collected for serum uric acid and followed till the birth of the baby. RESULTS: The study included age ranged from 18 up to 40 years. Average age was 28.69years +5.01SD. Sensitivity & specificity of uric acid level in Serum in diagnosis of low birth weight are 85.71% and 81.42% respectively while it has positive predictive & negative predictive value of 51.43% & 96.13% respectively. Diagnostic accuracy of uric acid level in serum was 82.22%. CONCLUSION: Uric acid level in serum is of great diagnostic and prognostic importance in women with pre-eclampsia & helps in predicting low birth weight.

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评估血清尿酸水平对子痫前期低出生体重的预测价值

目的：评估子痫前期女性血清尿酸水平升高在预测低出生体重方面的诊断准确性。研究对象和方法：横断面研究在伊斯兰堡 FGSH Poly 诊所妇科进行，研究时间为 2021 年 7 月 21 日至 2022 年 1 月 20 日，为期 6 个月。共有 225 名子痫前期孕妇接受了临床检查并被纳入研究。采集血样检测血清尿酸，并跟踪至婴儿出生。结果：研究对象的年龄从 18 岁到 40 岁不等。平均年龄为 28.69 岁 +5.01SD。血清尿酸水平对低出生体重儿诊断的敏感性和特异性分别为 85.71% 和 81.42%，阳性预测值和阴性预测值分别为 51.43% 和 96.13%。血清中尿酸水平的诊断准确率为 82.22%。结论：血清中的尿酸水平对子痫前期妇女的诊断和预后具有重要意义，并有助于预测低出生体重。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of Rawalpindi Medical College

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24 weeks