Exploring the Interplay of AHD, TB, and Cryptococcal Antigen in Nasarawa State

Olufunmilola Abodunde, Folake Isona, Oluwasola Oni, Chinwe Umeozulu, Kayode Joseph, Faith Audu, Hafsat Usman, Adeniyi Ojuope, Temitope Olayemi, Esther Loyin
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Abstract

This study explored the existing relationships between Advanced HIV Disease (AHD), Tuberculosis (TB), and Cryptococcal Antigen (CrAg) among People Living with HIV (PLHIV) in Nasarawa State, Nigeria. This was achieved by investigating the relationship and prevalence of TB and CrAg among individuals diagnosed with AHD in Nasarawa State; and by assessing the distribution and association of demographic characteristics of the study population with TB and Cryptococcal Antigen. This study employed a cross-sectional survey design, sampling respondents across different demographics at the same time. The study sample were individuals who are currently receiving antiretroviral treatment from our healthcare facilities in Nasarawa State, Nigeria. Results showed that TB and CrAg has low prevalence among the study population, however, compared to a larger population, this will be a serious concern. The study also suggest that the demographic information of the study population had no significant relationship on the development or presence of TB or CrAg, however, the study was ableto establish that PLHIVs who had AHD were mostly women (59.8%) in the State. Recommendation were made based on the study findings and the study concluded that the existing relationships among the study variables were not impacted significantly by either age or gender of the population.
探索纳萨拉瓦州急性呼吸道感染、结核病和隐球菌抗原的相互作用
本研究探讨了尼日利亚纳萨拉瓦州艾滋病毒感染者(PLHIV)中艾滋病晚期(AHD)、结核病(TB)和隐球菌抗原(CrAg)之间的现有关系。为此,研究人员调查了纳萨拉瓦州被诊断为艾滋病病毒感染者的人群中结核病和 CrAg 的关系和流行情况,并评估了研究人群的人口统计学特征与结核病和隐球菌抗原的分布和关联。本研究采用横断面调查设计,同时对不同人口统计学特征的受访者进行抽样调查。研究样本是目前正在尼日利亚纳萨拉瓦州医疗机构接受抗逆转录病毒治疗的个人。结果显示,结核病和 CrAg 在研究人群中的流行率较低,但与更大范围的人群相比,这将是一个严重问题。研究还表明,研究人群的人口统计学信息与肺结核或 CrAg 的发生或存在没有显著关系,但研究证实,该州患有 AHD 的艾滋病毒携带者大多为女性(59.8%)。根据研究结果提出了建议,研究得出结论认为,研究变量之间的现有关系并未受到人群年龄或性别的显著影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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