Quarter-Century Experience in Cryopreservation of Human Oocytes by Vitrifi cation. What Has Been Achieved and What is Next?

Q4 Medicine

Problems of Cryobiology and Cryomedicine Pub Date : 2023-09-30 DOI:10.15407/cryo33.03.177

T. Yurchuk, M. Petrushko

引用次数: 0

Abstract

Cryopreservation of human oocytes by the vitrification has become a part of the daily practice of assisted reproductive technologies to fight an infertility and to preserve the woman's reproductive potential. This literature review covers the results of the studies performed by various scientific schools during 25 years; historical prerequisites for the development of cryopreservation of human oocytes by vitrification; medical and social indices to apply this method, features and complications arising during vitrification of human oocytes. Special attention has been paid to the issues regarding the genetic safety of the method mentioned in respect of the health of future descendants. The paper presents the insight on unsolved tasks in vitrification of oocytes and that of identified ways to overcome the challenges.

查看原文本刊更多论文

通过玻璃化冷冻保存人类卵母细胞的四分之一世纪经验。已取得的成就和下一步计划？

通过玻璃化技术冷冻保存人类卵母细胞已成为辅助生殖技术日常实践的一部分，以对抗不孕症和保护妇女的生殖潜能。这篇文献综述涵盖了 25 年来不同科学流派的研究成果；玻璃化冷冻保存人类卵母细胞的历史先决条件；应用这种方法的医学和社会指标；人类卵母细胞玻璃化过程中出现的特征和并发症。论文还特别关注了该方法在遗传安全方面的问题，这关系到未来后代的健康。论文介绍了卵母细胞玻璃化过程中尚未解决的问题，以及克服这些挑战的方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Problems of Cryobiology and Cryomedicine Medicine-Medicine (miscellaneous)

CiteScore

0.60

自引率

0.00%

发文量

期刊介绍： The Journal publishes the reviews and original papers on cryobiological and cryomedical research, in particular the elucidation of mechanisms of injuries occurring in biological objects and caused by the influence of low and ultra low temperatures; natural resistance of biologicals to cold and their recovery post effect; the development of effective methods of cryoprotection and technology of storage of biological resources under hypothermic and ultra low temperatures, application of hypothermia, cryotherapy and cryopreserved biologicals for treating various pathologies; cell and tissue based therapies and other issues of low-temperature biology and medicine, as well as development of devices and equipment for low temperature biology and medicine. The journal covers all topics related to low temperature biology, medicine and engineering. These include but are not limited to: low temperature storage of biologicals (human, animal or plant cells, tissues, and organs), including preparation for storage, thawing/warming, cell and tissue culturing etc. response of biologicals to low temperature; cold adaptation of animals and plants; utilisation of low temperature in medicine; experimental and clinical transplantation, cell and tissue based therapies; developing of cryobiological and cryomedical devices; organisation and functioning of low temperature banks etc.