CHEMICAL COMPOSITION AND BIOLOGICAL PROPERTIES OF THE KIDNEYS OF POPULUS NIGRA L. OF THE CASPIAN REGION

Lyudmila Timofeyevna Sukhenkо, Evgeny Alexandrovich Kurashov, Yuliya Viktorovna Krylova
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Abstract

The chemical composition of low molecular weight organic compounds (NOS) was studied by chromatography-mass spectrometric analysis of Populus nigra L. kidneys. Of the Caspian region and comparative antimicrobial (bactericidal) activity of extractive components with other plants with characteristic antimicrobial properties. The extraction was carried out by percolation in water-alcohol solutions. The study of antimicrobial activity was carried out by the standard CFU method. As a result, 49 compounds were identified, of which 10 remained unidentified. The study of comparative antimicrobial properties of plant extracts showed the complete bactericidal activity of Populus nigra kidneys against opportunistic microorganisms and microflora of air and water, in MIC equal to 0.25 micrograms/ml. Therefore, the NOSES isolated from the kidneys of Populus nigro of the Caspian region have prospects for further study of antioxidant activity for the preparation of biotechnological drugs and pharmaceutical substances.
里海地区黑杨肾脏的化学成分和生物特性
通过色谱-质谱分析法研究了黑杨肾脏中低分子量有机化合物(NOS)的化学成分。并将萃取成分的抗菌(杀菌)活性与其他具有抗菌特性的植物进行了比较。萃取是在水-酒精溶液中通过渗滤法进行的。抗菌活性研究采用标准 CFU 法进行。结果鉴定出 49 种化合物,其中 10 种尚未鉴定。对植物提取物抗菌特性的比较研究表明,黑杨肾脏对机会性微生物以及空气和水中的微生物菌群具有完全的杀菌活性,MIC 值等于 0.25 微克/毫升。因此,从里海地区的黑杨肾脏中分离出的 NOSES 具有进一步研究抗氧化活性的前景,可用于制备生物技术药物和医药物质。
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