Modern Treatment of Bacterial Vaginosis in the Second Trimester of Pregnancy

Effective Pharmacotherapy Pub Date : 2023-10-19 DOI:10.33978/2307-3586-2023-19-37-6-10

N. Z. Mammaeva, I. B. Manukhin, S.D. Osmanova

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Abstract

Purpose: to assess the effectiveness of modern methods of treatment of patients with BV in the second trimester of pregnancy. Material and methods. The prospective comparative study included 50 patients of the second trimester of pregnancy with BV, which are divided into 2 groups. The first group received clindamycin + Lactoginal at the same time. The second group received the probiotc Lactoginal. Microscopic examination of the vaginal smear and PCR diagnostics were performed in all pregnant women. After treatment, a second study was carried out on the vaginal microflora in pregnant women. Results. According to the results of the study: according to the Amsel criterion, the recovery of patients in group 1 was 88%, in group 2 – 84%. According to the PCR study in group 1 – 80%, in group 2 – 76%. After the therapy, none of the patients noted clinical complaints. In the study groups, in 42 patients, pregnancy ended in timely delivery; caesarean section in 8 patients. Conclusion. The use of a probiotic in pregnant women with BV separately is an alternative method of treatment, favorably affects the entire period of pregnancy, as well as subsequently on delivery

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妊娠后三个月细菌性阴道病的现代治疗方法

目的：评估治疗妊娠后三个月 BV 患者的现代方法的有效性。材料和方法。前瞻性比较研究纳入了 50 名妊娠后三个月的 BV 患者，分为两组。第一组同时接受克林霉素+乳果糖。第二组接受益生菌 Lactoginal。对所有孕妇进行阴道涂片显微镜检查和 PCR 诊断。治疗后，对孕妇的阴道微生物菌群进行了第二次研究。结果显示研究结果显示：根据 Amsel 标准，第一组患者的康复率为 88%，第二组为 84%。根据聚合酶链式反应（PCR）研究，第一组为 80%，第二组为 76%。治疗后，没有一名患者出现临床症状。在研究组中，42 名患者的妊娠以及时分娩结束；8 名患者进行了剖腹产。结论对患有 BV 的孕妇单独使用益生菌是一种替代治疗方法，对整个孕期以及随后的分娩都会产生有利影响。

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Effective Pharmacotherapy

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