Pathophysiological Mechanisms of FHA and PCOS in Girls of Reproductive Age

Abstract

Secondary oligo-/amenorrhea occurs in 3–5% of women of reproductive age. The two most common causes are polycystic ovary syndrome (PCOS) (2–13%) and functional hypothalamic amenorrhea (FHA) (1–2%). The goal of this literature review was to study and systematize data from foreign relevant l studies on the topic as differences in the pathophysiological mechanisms of FHA and PCOS. The topic touched upon is important and requires analysis due to the difficulty of understanding and the still unclear pathophysiology of FHA and PCOS. This review examines the mechanisms of ovarian dysfunction in PHA and PCOS as the main causes of menstrual cycle disorders.