Challenges, Biases, and Limitations in Systematic Reviews and Meta-Analyses: Addressing Pitfalls inMedical Research Methodologies

Abstract

Systematic reviews and meta-analyses represent crucial tools in medical research, synthesizing vast arrays of data toinform clinical and policy decisions. While their merits are undeniable, potential pitfalls, biases, and limitationsthreaten the integrity of these methodologies. This paper explores common challenges faced in the execution andinterpretation of systematic reviews and meta-analyses, emphasizing strategies to enhance the robustness andreliability of future research. Keywords: Systematic Reviews, Meta-Analysis, Biases, Limitations, Medical Research Methodologies