MicroRNA miR-204-5p IS A REGULATOR OF APOPTOSIS IN DACARBAZINE-RESISTANT MELANOMA CELLS

Cardiometry Pub Date : 2023-11-01 DOI:10.18137/cardiometry.2023.29.conf.19

N.V. Palkina

引用次数: 0

Abstract

Therapy for skin melanoma in its disseminated form is ineffective, among other things, due to the development of tumor cell resistance, mediated by various mechanisms. The acquisition of a stable cell phenotype is associated both with genetic and epigenetic changes mediated by the regulatory non-coding microRNA molecules.

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微RNA miR-204-5p 是抗达卡巴嗪骨髓细胞凋亡的调节因子

对扩散型皮肤黑色素瘤的治疗效果不佳，主要是因为肿瘤细胞在各种机制的介导下产生了抗药性。获得稳定的细胞表型既与遗传有关，也与由非编码微 RNA 调控分子介导的表观遗传变化有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cardiometry MEDICAL LABORATORY TECHNOLOGY-

自引率

0.00%

发文量

审稿时长

6 weeks

期刊介绍： Cardiometry is an open access biannual electronic journal founded in 2012. It refers to medicine, particularly to cardiology, as well as oncocardiology and allied science of biophysics and medical equipment engineering. We publish mainly high quality original articles, reports, case reports, reviews and lectures in the field of the theory of cardiovascular system functioning, principles of cardiometry, its diagnostic methods, cardiovascular system therapy from the aspect of cardiometry, system and particular approaches to maintaining health, engineering peculiarities in cardiometry developing. The interdisciplinary areas of the journal are: hemodynamics, biophysics, biochemistry, metrology. The target audience of our Journal covers healthcare providers including cardiologists and general practitioners, bioengineers, biophysics, medical equipment, especially cardiology diagnostics device, developers, educators, nurses, healthcare decision-makers, people with cardiovascular diseases, cardiology and engineering universities and schools, state and private clinics. Cardiometry is aimed to provide a wide forum for exchange of information and public discussion on above scientific issues for the mentioned experts.