Chronic gastritis in pediatrics

Cardiometry Pub Date : 2023-11-01 DOI:10.18137/cardiometry.2023.29.5461

N.V. Gabueva, V.S. Kalinchuk, D.R. Radchenko, S.A. Donchenko, A.A. Panesh, S.A. Popov

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引用次数: 0

Abstract

Chronic gastritis is one of the most common diseases of the gastrointestinal tract. High rates of gastritis in children are associated with poor nutrition, physical inactivity, drug abuse, bad habits, a number of concomitant diseases, immune disorders, allergization of the body, and stress. Although a significant proportion in the structure of chronic gastritis is occupied by gastritis associated with Helicobacter pylori infection, many clinical forms are diagnosed that are not associated with the presence of a microbial pathogen in the gastric mucosa. The goal is to highlight the problem of chronic gastritis in children, including risk factors, etiology, clinical manifestations, diagnosis and treatment. Materials and methods. To achieve these goals, a literature search was carried out in the PubMed and Google Scholar databases. The search depth did not exceed 5 years. Uninformative and duplicate articles were excluded. The final list of references included 42 articles. Results. In addition to traditional risk factors for adults, the incidence of chronic gastritis in children is influenced by artificial feeding, pathology of pregnancy and childbirth, respiratory infections, decreased mobility, and concomitant pathology. Helicobacter pylori infection is detected in 56% of children referred to a gastroenterologist for gastrointestinal symptoms. Manifestations of gastritis vary from asymptomatic to epigastric pain with dyspeptic symptoms. Conclusion. 1) Currently, up to 30-40% of children suffer from chronic gastritis. 2) Triple therapy regimens are traditionally used to eradicate Helicobacter pylori, but quadruple therapy is used in populations with high resistance to antimicrobial drugs. 3) In the treatment of eosinophilic gastritis, the drugs benralizumab and vedolizumab demonstrate high effectiveness, leading to depletion of the pool of eosinophils in the blood and tissues of the stomach, as well as clinical improvement. 4) Effective treatment for collagen gastritis has not yet been developed. The treatment regimen includes an elimination diet, proton pump inhibitors, and iron supplements.

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儿科慢性胃炎

慢性胃炎是胃肠道最常见的疾病之一。儿童胃炎发病率高与营养不良、缺乏运动、滥用药物、不良生活习惯、多种并发症、免疫功能紊乱、身体过敏和精神压力有关。虽然与幽门螺旋杆菌感染相关的胃炎在慢性胃炎的结构中占有很大比例，但也有许多与胃黏膜中微生物病原体的存在无关的临床诊断形式。本文旨在强调儿童慢性胃炎的问题，包括危险因素、病因、临床表现、诊断和治疗。材料和方法。为实现上述目标，我们在 PubMed 和 Google Scholar 数据库中进行了文献检索。搜索深度不超过 5 年。排除了信息不全和重复的文章。最终的参考文献列表包括 42 篇文章。研究结果除了成人的传统风险因素外，儿童慢性胃炎的发病率还受到人工喂养、妊娠和分娩病理、呼吸道感染、活动能力下降以及并发病理等因素的影响。在因胃肠道症状而转诊到消化科的儿童中，56%的儿童被检测出感染幽门螺杆菌。胃炎的表现多种多样，从无症状到上腹痛并伴有消化不良症状。结论1) 目前，多达 30-40% 的儿童患有慢性胃炎。2) 传统上采用三联疗法根除幽门螺旋杆菌，但在抗菌药物耐药性较强的人群中则采用四联疗法。3) 在嗜酸性粒细胞性胃炎的治疗中，药物 benralizumab 和 vedolizumab 显示出很高的疗效，可使胃部血液和组织中的嗜酸性粒细胞库枯竭，临床症状也得到改善。4) 胶原性胃炎的有效治疗方法尚未开发出来。治疗方案包括消除性饮食、质子泵抑制剂和铁质补充剂。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cardiometry MEDICAL LABORATORY TECHNOLOGY-

自引率

0.00%

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审稿时长

6 weeks

期刊介绍： Cardiometry is an open access biannual electronic journal founded in 2012. It refers to medicine, particularly to cardiology, as well as oncocardiology and allied science of biophysics and medical equipment engineering. We publish mainly high quality original articles, reports, case reports, reviews and lectures in the field of the theory of cardiovascular system functioning, principles of cardiometry, its diagnostic methods, cardiovascular system therapy from the aspect of cardiometry, system and particular approaches to maintaining health, engineering peculiarities in cardiometry developing. The interdisciplinary areas of the journal are: hemodynamics, biophysics, biochemistry, metrology. The target audience of our Journal covers healthcare providers including cardiologists and general practitioners, bioengineers, biophysics, medical equipment, especially cardiology diagnostics device, developers, educators, nurses, healthcare decision-makers, people with cardiovascular diseases, cardiology and engineering universities and schools, state and private clinics. Cardiometry is aimed to provide a wide forum for exchange of information and public discussion on above scientific issues for the mentioned experts.