I. I. Khan, A. S. Latysheva, V. A. Zolottsev, Elena A. Demidova, Tatyana S. Spirina, Saida S. Karshieva, D. Sokolova, M. N. Yakunina, A. Misharin, Marina V. Komarova, V. Pokrovsky
{"title":"Antiproliferative activity of the novel CYP17A1 inhibitor alsevirone","authors":"I. I. Khan, A. S. Latysheva, V. A. Zolottsev, Elena A. Demidova, Tatyana S. Spirina, Saida S. Karshieva, D. Sokolova, M. N. Yakunina, A. Misharin, Marina V. Komarova, V. Pokrovsky","doi":"10.17816/onco492271","DOIUrl":null,"url":null,"abstract":"Abstract Background: Prostate cancer (PC) is the most frequently diagnosed type of cancer in men in developed countries. PC is dependent upon androgens and could be effectively combated by androgen deprivation therapy in such patients. Reduction of androgen synthesis can be accomplished through the inhibition of the enzyme 17","PeriodicalId":509207,"journal":{"name":"Russian Journal of Oncology","volume":"6 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17816/onco492271","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract Background: Prostate cancer (PC) is the most frequently diagnosed type of cancer in men in developed countries. PC is dependent upon androgens and could be effectively combated by androgen deprivation therapy in such patients. Reduction of androgen synthesis can be accomplished through the inhibition of the enzyme 17