Antimicrobial Screening of the Solvent Extracts of Marchantia polymorpha against Some Pathogenic Strains

K. P. Lakshmi, G. Rao
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Abstract

Marchantia polymorpha is a shade loving species of bryophytes prefers to grow in low temperature and moderate humidity, where presence of thick forest canopy. Marchania polymorpha used in tribal regions for several medicinal applications. Based on its importance, this species is evaluated for antimicrobial activity against four bacterial stains such as Bacillus subtilis and Streptococcus mutans (Gram positive), Klebsiella pneumonia and Salmonella enterica (Gram negative) and two fungal pathogens such as Candida albicans, Rhizopus oryzae) by Agar Well Diffusion method. Plant extracts were obtained successfully with hexane, chloroform, methanol and water using Soxhlet extraction apparatus. Results of this study reveal that methanol extracts of M. polymorpha thallus showed the significant antimicrobial activity against all bacterial and fungal pathogens. These studies on bryophyte species indicated that the presence of active constituents which can be exploited for the production of novel drugs for the benefit of the humanity.
马钱子溶剂提取物对一些致病菌株的抗菌筛选
马钱子是一种喜阴的苔藓植物,喜欢生长在低温、湿度适中、林冠茂密的地方。马钱子在部落地区有多种药用用途。基于其重要性,本研究采用琼脂井扩散法评估了该物种对四种细菌(如枯草芽孢杆菌和变异链球菌(革兰氏阳性)、肺炎克雷伯氏菌和肠炎沙门氏菌(革兰氏阴性))以及两种真菌(如白色念珠菌和根瘤菌)的抗菌活性。使用索氏萃取器成功地用正己烷、氯仿、甲醇和水提取了植物提取物。研究结果表明,M. polymorpha 苔藓的甲醇提取物对所有细菌和真菌病原体都有显著的抗菌活性。这些关于叶绿体物种的研究表明,其中存在的活性成分可用于生产新型药物,造福人类。
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