SYNTHESIS OF 2-FLUOROBENZOYL THIOUREA DERIVATIVES

Abstract

In this study, a series of 2-fluorobenzoyl thiourea derivatives were synthesized by the reaction of 2-fluorobenzoyl isothiocyanate, which was obtained by the reaction of 2-fluorobenzoyl chloride with ammonium thiocyanate, with appropriate aniline derivatives. The structures of the synthesized compounds were confirmed by 1H NMR, 13C NMR and IR spectroscopy.