Clinical Spectrum of Dengue in a Tertiary Care Hospital of Northern Bangladesh

A. Rizwan, Shahida Akhter
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Abstract

Background: Dengue is an emerging major infectious disease which causes frequent outbreaks affecting millions. The complex interplay between virus serotype, host immune response and environmental factor set a series of changes in dengue presentation over the years. Materials and method: This was a cross-sectional, observational study conducted on 100 diagnosed dengue patients attending a tertiary teaching hospital. The study participants were divided into severe and non-severe categories and compared in terms of their symptoms, severity and lab findings. Statistical analysis was done using SPSS. Result: Majority of the study participants were younger. Female participants were more than male. Apart from fever, headache was found to be the commonest symptom in general. Epistaxis and melaena were significantly higher among severe group than non-severe peers. Gastrointestinal symptoms were frequently present among both groups. Conclusion: Most of the cases of dengue patient didn’t suffer from life threatening infection but when the infection is severe, bleeding manifestation can be a predictor of the onset of critical illness. J Bangladesh Coll Phys Surg 2023; 41: 34-38
孟加拉国北部一家三级医院的登革热临床表现
背景:登革热是一种新出现的主要传染病,经常爆发,影响数百万人。多年来,病毒血清型、宿主免疫反应和环境因素之间复杂的相互作用使登革热的表现形式发生了一系列变化。材料和方法:这是一项横断面观察研究,研究对象是在一家三级教学医院就诊的 100 名登革热确诊患者。研究参与者被分为严重和非严重两类,并在症状、严重程度和实验室检查结果方面进行了比较。使用 SPSS 进行了统计分析。研究结果大多数研究参与者较为年轻。女性参与者多于男性。除发热外,头痛是最常见的症状。重症组的鼻衄和血淤明显高于非重症组。两组患者都经常出现胃肠道症状。结论大多数登革热病人并没有受到危及生命的感染,但当感染严重时,出血表现可能是危重病发作的预兆。J Bangladesh Coll Phys Surg 2023; 41: 34-38
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