Asymmetric electrochemical synthesis in flow

IF 2 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY
Daniele Mazzarella
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Abstract

We are currently experiencing a resurgence in the realm of electrochemical organic synthesis, driven by the transformative potential of conducting redox chemistry under mild conditions through the simple use of electrons, thereby circumventing the use of harmful reductants and oxidants. This renaissance is further bolstered by the fusion of electrochemistry with flow chemistry, which not only grants precise control over reaction parameters but also promotes sustainability and heightened reproducibility. Despite these promising advancements, the application of flow electrochemistry to steer asymmetric processes remains in its nascent stage. This perspective delves into the limited contributions to date, shedding light on critical challenges and presenting prospective solutions that are essential for fully unleashing the untapped potential of this field.

Graphical abstract

Abstract Image

流动中的不对称电化学合成
目前,我们正在经历电化学有机合成领域的复兴,其驱动力是通过简单使用电子,在温和条件下进行氧化还原化学反应的变革潜力,从而避免使用有害的还原剂和氧化剂。电化学与流动化学的融合进一步推动了这一复兴,它不仅能精确控制反应参数,还能促进可持续性和提高可重复性。尽管取得了这些令人鼓舞的进展,但将流动电化学应用于引导不对称过程的研究仍处于起步阶段。本视角深入探讨了迄今为止的有限贡献,揭示了关键挑战并提出了前瞻性解决方案,这对于充分释放该领域尚未开发的潜力至关重要。
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来源期刊
Journal of Flow Chemistry
Journal of Flow Chemistry CHEMISTRY, MULTIDISCIPLINARY-
CiteScore
6.40
自引率
3.70%
发文量
29
审稿时长
>12 weeks
期刊介绍: The main focus of the journal is flow chemistry in inorganic, organic, analytical and process chemistry in the academic research as well as in applied research and development in the pharmaceutical, agrochemical, fine-chemical, petro- chemical, fragrance industry.
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