Clinical Analysis of 128 Children and Adolescents with Echinococcosis

Linghong Zhu, Yanqing Ma, Yongmei Lan, Zilong Zhang
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Abstract

Objective: To comprehend the clinical characteristics and treatment approaches for children and adolescents in Qinghai Province with two types of echinococcosis, cystic echinococcosis (CE) and alveolar echinococcosis (AE). Methods: A total of 128 pediatric inpatients with echinococcosis at the People’s Hospital of Qinghai Province and the Clinical Research Institute of Echinococcosis of Qinghai Province between January 2016 and December 2021 were chosen as subjects. Demographic and clinical data were collected, and double data entry was executed using EpiData 3.02. Factors influencing the cure of echinococcosis were analyzed with echinococcosis cure as the dependent variable, employing statistical analysis via SPSS 19.0. Results: Of the cases, 35.9% had CE, and 64.1% had AE. Both types were observed in patients of all ages, with the majority aged 13–18. The number of cysts and their sizes varied between CE and AE. Complications were prevalent, including liver, gallbladder, lung, and nutritional complications. Univariate analyses revealed significant differences in outcomes based on factors such as cyst size (for CE), liver function grade (for AE), hydatid hypersensitivity test, operation, and length of hospital stay (P < 0.05). Conclusion: This comprehensive analysis of hospitalized cases sheds light on the clinical data of echinococcosis in children and adolescents in Qinghai Province. The findings contribute to a scientific foundation for formulating effective prevention and control measures tailored to this demographic, facilitating an improved understanding of echinococcosis in Qinghai province.
128 名儿童和青少年棘球蚴病患者的临床分析
目的了解青海省儿童和青少年两种类型棘球蚴病(囊状棘球蚴病(CE)和肺泡棘球蚴病(AE))的临床特点和治疗方法。研究方法选取2016年1月至2021年12月期间在青海省人民医院和青海省棘球蚴病临床研究所住院的128名儿科棘球蚴病患者作为研究对象。收集人口统计学和临床数据,并使用 EpiData 3.02 进行双重数据录入。以棘球蚴病治愈率为因变量,通过 SPSS 19.0 进行统计分析,分析影响棘球蚴病治愈率的因素。结果病例中,35.9% 患有 CE,64.1% 患有 AE。所有年龄段的患者都有这两种类型,其中大多数患者的年龄在 13-18 岁之间。CE和AE的囊肿数量和大小各不相同。并发症很普遍,包括肝、胆囊、肺和营养并发症。单变量分析显示,囊肿大小(CE)、肝功能分级(AE)、包虫病超敏试验、手术和住院时间等因素导致的结果存在显著差异(P < 0.05)。结论对住院病例的综合分析揭示了青海省儿童和青少年棘球蚴病的临床数据。研究结果为针对该人群制定有效的预防和控制措施奠定了科学基础,有助于加深对青海省棘球蚴病的了解。
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