Results of treatment of recurrent growth and metastasis of anaplastic gliomas

Abstract

Anaplastic glioma is one of the most dangerous and serious brain tumors. Modern microsurgery, radiation, chemotherapy, and other all-encompassing therapeutic techniques can lead to inadequate clinical treatment results for gliomas. High dose re-irradiation with concurrent chemotherapy is a workable treatment option for patients with metastases and recurrent anaplastic gliomas, even when significant treatment volumes are being employed to target non-enhancing tumor components. The issue of glioma metastasis is likewise unsettled and poorly understood. Single serial observations of high-grade glioma metastases are reported in the international literature, with glioblastoma accounting for the majority of these cases. Isolated cases of anaplastic glioma metastasis have been recorded in the majorit y of observations.