Evaluation of upper limb lymphoedema and diagnostic accuracy of bioimpedance spectroscopy. A comprehensive validation in a Brazilian population

ecancermedicalscience Pub Date : 2023-12-18 DOI:10.3332/ecancer.2023.1649

Fabíola C Brandini da Silva Tozzo, A. Sarri, Willian Eduardo Pirola, Uliana Basilio Cardoso da Silva, Marco Antonio de Oliveira, Cristiano de Pádua Souza, R. A. da Costa Vieira

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Abstract

Lymphoedema is a complication of breast cancer treatment. Its early diagnosis is related to a good prognosis for lymphoedema treatment. The bioimpedance spectroscopy (BIS) evaluates changes in extracellular fluid. The objective of our study was to evaluate the validity, agreement and accuracy of BIS in the diagnosis of breast cancer-related lymph-oedema in a Brazilian population. Methods: This is a prospective, cross-sectional study of a convenience sample of 462 women who underwent surgical treatment for breast cancer (mastectomy or breast-conserving treatment). The validity, agreement and accuracy were performed comparing BIS (lymphoedema index (L-DEX) ≥ 6.5 or 10) with volumetry by water displacement, which is the gold standard for evaluating lymphoedema. Receiver operating characteristic curve was performed. Additionally, other methods like perimetry and indirect volumetry of the upper limbs were compared with water displacement volumetry (direct volumetry)

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评估上肢淋巴水肿和生物阻抗光谱仪的诊断准确性。在巴西人群中进行全面验证

淋巴水肿是乳腺癌治疗的一种并发症。淋巴水肿的早期诊断关系到淋巴水肿治疗的良好预后。生物阻抗光谱（BIS）可评估细胞外液的变化。我们的研究旨在评估生物阻抗频谱仪在巴西人群中诊断乳腺癌相关淋巴水肿的有效性、一致性和准确性。研究方法这是一项前瞻性横断面研究，研究对象是 462 名接受过乳腺癌手术治疗（乳房切除术或保乳治疗）的女性。将 BIS（淋巴水肿指数（L-DEX）≥ 6.5 或 10）与水排量测量法（评估淋巴水肿的金标准）进行了有效性、一致性和准确性比较。进行了接收者操作特征曲线分析。此外，还将其他方法如周径测量法和上肢间接容积测量法与水位移容积测量法（直接容积测量法）进行了比较。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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ecancermedicalscience

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