Features of cytomegalovirus infection in severely premature newborns

O. V. Lebedeva, N. Pimenova, E. Kashirskaya, T. A. Berezhnova, E. Polyanina, T. A. Gasanova
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Abstract

Cytomegalovirus infection of newborns is one of the serious medical and social problems of neonatology and is often the cause of disability and mortality of the child population.The purpose of the work was to study the incidence and clinical characteristics of cytomegalovirus infection in very premature newborns.  Materials and methods. Data from 384 medical records of premature infants with a gestational age of less than 32 weeks were analyzed.Results. The variants of the clinical course of the disease are described, the results of laboratory studies are presented, as well as the methods of therapy used. Clinical cases with fatal outcome demonstrated. The results of the study showed that the postnatal form of the disease was 3 times more common than congenital and often occurred under the “mask” of another severe pathology, which made early diagnosis difficult. For timely diagnosis and treatment of cytomegalovirus infection in severely premature newborns, regular polymerase chain reaction examination is recommended.
严重早产新生儿巨细胞病毒感染的特征
新生儿巨细胞病毒感染是新生儿科严重的医学和社会问题之一,通常是导致儿童残疾和死亡的原因。这项工作的目的是研究极早产新生儿巨细胞病毒感染的发病率和临床特征。 材料和方法对 384 份胎龄小于 32 周的早产儿病历数据进行了分析。描述了该病临床过程的变异,介绍了实验室研究的结果以及采用的治疗方法。展示了致命的临床病例。研究结果表明,产后型该病的发病率是先天型的三倍,而且往往是在其他严重病症的 "掩盖 "下发生的,这给早期诊断带来了困难。为了及时诊断和治疗严重早产新生儿巨细胞病毒感染,建议定期进行聚合酶链反应检查。
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