Features of cytomegalovirus infection in severely premature newborns

Abstract

Cytomegalovirus infection of newborns is one of the serious medical and social problems of neonatology and is often the cause of disability and mortality of the child population.The purpose of the work was to study the incidence and clinical characteristics of cytomegalovirus infection in very premature newborns.  Materials and methods. Data from 384 medical records of premature infants with a gestational age of less than 32 weeks were analyzed.Results. The variants of the clinical course of the disease are described, the results of laboratory studies are presented, as well as the methods of therapy used. Clinical cases with fatal outcome demonstrated. The results of the study showed that the postnatal form of the disease was 3 times more common than congenital and often occurred under the “mask” of another severe pathology, which made early diagnosis difficult. For timely diagnosis and treatment of cytomegalovirus infection in severely premature newborns, regular polymerase chain reaction examination is recommended.