A Rare Case of Panton-Valentine Leukocidin-Related Cervical Empyema

Hung Le, Dung Le Thuy Nguyen, My Nu Tra Ton, Duy Phan, Anh Hoang Ngoc Tran, Van Tri Truong
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Abstract

Abstract Staphylococcus aureus is found in the normal skin and mucosa of approximately 30% of healthy populations and is the most common pathogen in human disease associated with bacteria. They are divided into methicillin-sensitive S . aureus (MSSA) and methicillin-resistant S. aureus (MRSA). The S. aureus strains carrying the Panton-Valentine leukocidin genes (SA-PVL) were initially believed to belong to the MRSA group; however, recent reports showed they also belonged to the MSSA group (MSSA-PVL). SA-PVL is common in skin and soft-tissue infections but rare in musculoskeletal infections, especially in spondylodiscitis. We are reporting a case suffering from cervical spondylodiscitis and epidural abscess associated with MSSA carrying the Panton-Valentine leukocidin genes.
潘顿-瓦伦丁白细胞介素相关性颈椎水肿的罕见病例
摘要 金黄色葡萄球菌存在于约 30% 健康人群的正常皮肤和粘膜中,是人类疾病中最常见的细菌病原体。金黄色葡萄球菌分为对甲氧西林敏感的金黄色葡萄球菌(MSSA)和对甲氧西林耐药的金黄色葡萄球菌(MRSA)。携带潘顿-瓦伦丁白细胞介素基因(SA-PVL)的金黄色葡萄球菌菌株最初被认为属于 MRSA 组,但最近的报告显示它们也属于 MSSA 组(MSSA-PVL)。SA-PVL 常见于皮肤和软组织感染,但罕见于肌肉骨骼感染,尤其是脊柱盘炎症。我们报告了一例颈椎盘炎和硬膜外脓肿病例,该病例与携带潘顿-瓦伦丁白细胞介素基因的 MSSA 有关。
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