Optimization of chronic periodontitis comprehensive treatment

A. I. Bulgakov, E. S. Soldatova, Yu. O. Kuvardina
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Abstract

Relevance. The increasing prevalence of mild to moderate chronic generalized periodontitis depends on endogenous and exogenous factors. In most cases, these include factors such as fair oral hygiene, oral microbiota characteristics, increased loads on periodontium, malocclusion, smoking, history of systemic disorders, genetic predisposition, neuroses, etc. Despite the variety of available treatment protocols for mild to moderate chronic generalized periodontitis, the result has a short-term effect. Thus, searching for new treatment algorithms and creating improved medications with the necessary properties to stabilize the process and prolong remission in chronic periodontitis are relevant.The study aimed to evaluate the effectiveness of the comprehensive chronic periodontitis treatment with netilmicin ointment and propolis extract combined with diode laser, considering periodontal and immune statuses.Material and methods. The study involved 70 patients with mild and moderate chronic generalized periodontitis and 30 controls without signs of inflammatory periodontal diseases (IPD). The main group consisted of 50 patients with IPD, who had comprehensive treatment with the ointment based on netilmicin and propolis extract and antiinflammatory therapy using the Doctor Smile diode laser. The comparison group comprised 20 patients whose treatment protocol did not include laser treatment. We conducted a clinical and immunological study of patients before and after the treatment.Results. The comprehensive treatment evaluation, including clinical and immunological analysis, revealed a significant improvement in the parameters when using a combination of ointment with netilmicin/propolis extract and laser therapy, compared to standard non-surgical treatment.Conclusion. The clinical and immunological analysis of the comprehensive treatment of patients with chronic periodontitis has established the advantage of the combined use of non-surgical treatment and physiotherapy procedures.
优化慢性牙周炎的综合治疗
相关性。轻度至中度慢性全身性牙周炎的发病率不断上升取决于内源性和外源性因素。在大多数情况下,这些因素包括口腔卫生状况不佳、口腔微生物群特征、牙周负荷增加、咬合不正、吸烟、全身性疾病史、遗传倾向、神经官能症等。尽管针对轻度至中度慢性泛发性牙周炎的治疗方案多种多样,但效果都是短期的。因此,寻找新的治疗方案和创造具有必要特性的改良药物以稳定慢性牙周炎的治疗过程并延长缓解期具有重要意义。本研究旨在评估使用奈替米星软膏和蜂胶提取物联合二极管激光治疗慢性牙周炎的综合疗效,同时考虑牙周和免疫状态。研究对象包括 70 名轻度和中度慢性泛发性牙周炎患者,以及 30 名无炎症性牙周病(IPD)症状的对照组患者。主组由 50 名 IPD 患者组成,他们接受了基于奈替米星和蜂胶提取物的软膏综合治疗,并使用 Doctor Smile 二极管激光器进行抗炎治疗。对比组包括 20 名患者,他们的治疗方案不包括激光治疗。我们在治疗前后对患者进行了临床和免疫学研究。包括临床和免疫学分析在内的综合治疗评估显示,与标准的非手术治疗相比,联合使用奈替米星/波罗的海萃取物软膏和激光治疗后,各项指标均有显著改善。通过对慢性牙周炎患者综合治疗的临床和免疫学分析,确定了联合使用非手术治疗和理疗程序的优势。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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