An uncommon case of metastatic undifferentiated pleomorphic soft tissue sarcoma during pregnancy: Literature review and case report

IF 1.5 Q3 OBSTETRICS & GYNECOLOGY

European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2023-12-28 DOI:10.1016/j.eurox.2023.100278

Valentina Sala , Giuliana Di Simone , Chiara Lubrano , Aida Quarenghi , Roberta Simona Rossi , Manuela Nebuloni , Irene Cetin

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引用次数: 0

Abstract

Soft tissue sarcomas accounts for 1–2% of adult malignancies. Undifferentiated pleomorphic sarcoma (UPS) is a rare subtype that lack immunohistochemical markers for a specific definition. About 18% of sarcomas are at a locally advanced stage, often requiring several cycles of chemotherapy and radiotherapy, in addition to surgery. For a young woman, this can mean delaying pregnancies with a high risk of therapy-induced ovarian damage. For this reason, proper counseling on fertility preservation plays a key role. In addition, all women of childbearing age with cancer, should be informed about the importance of planning a pregnancy to improve maternal and neonatal outcomes. We report a rare case of a 40-year-old woman with a UPS who, during CT scan after chemotherapy to decide on surgery, find out she was pregnant. After counseling, the patient decides to go ahead with the pregnancy.

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妊娠期转移性未分化多形性软组织肉瘤的罕见病例：文献综述与病例报告

软组织肉瘤占成人恶性肿瘤的 1-2%。未分化多形性肉瘤（UPS）是一种罕见的亚型，缺乏特定定义的免疫组化标记。约 18% 的肉瘤处于局部晚期，除了手术治疗外，通常还需要多个周期的化疗和放疗。对于年轻女性来说，这可能意味着要推迟怀孕，而治疗引起卵巢损伤的风险很高。因此，适当的生育保护咨询起着关键作用。此外，所有患有癌症的育龄妇女都应了解计划怀孕的重要性，以改善孕产妇和新生儿的预后。我们报告了一例罕见病例：一名 40 岁的 UPS 女性患者在化疗后进行 CT 扫描以决定是否手术时，发现自己怀孕了。经过咨询，患者决定继续妊娠。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Journal of Obstetrics and Gynecology and Reproductive Biology: X Medicine-Obstetrics and Gynecology

CiteScore

2.20

自引率

0.00%

发文量

审稿时长

58 days