{"title":"Transmission matrices used in epidemiologic modelling","authors":"M. Bekker-Nielsen Dunbar","doi":"10.1016/j.idm.2023.11.009","DOIUrl":null,"url":null,"abstract":"<div><p>Mixing matrices are included in infectious disease models to reflect transmission opportunities between population strata. These matrices were originally constructed on the basis of theoretical considerations and most of the early work in this area originates from research on sexually transferred diseases in the 80s, in response to AIDS. Later work in the 90s populated these matrices on the basis of survey data gathered to capture transmission risks for respiratory diseases. We provide an overview of developments in the construction of matrices for capturing transmission opportunities in populations. Such transmission matrices are useful for epidemiologic modelling to capture within and between stratum transmission and can be informed from theoretical mixing assumptions, informed by empirical evidence gathered through investigation as well as generated on the basis of data. Links to summary measures and threshold conditions are also provided.</p></div>","PeriodicalId":36831,"journal":{"name":"Infectious Disease Modelling","volume":null,"pages":null},"PeriodicalIF":8.8000,"publicationDate":"2023-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2468042723001057/pdfft?md5=d148717379ebdc2e453d384db9ce4fc4&pid=1-s2.0-S2468042723001057-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Infectious Disease Modelling","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2468042723001057","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Mixing matrices are included in infectious disease models to reflect transmission opportunities between population strata. These matrices were originally constructed on the basis of theoretical considerations and most of the early work in this area originates from research on sexually transferred diseases in the 80s, in response to AIDS. Later work in the 90s populated these matrices on the basis of survey data gathered to capture transmission risks for respiratory diseases. We provide an overview of developments in the construction of matrices for capturing transmission opportunities in populations. Such transmission matrices are useful for epidemiologic modelling to capture within and between stratum transmission and can be informed from theoretical mixing assumptions, informed by empirical evidence gathered through investigation as well as generated on the basis of data. Links to summary measures and threshold conditions are also provided.
期刊介绍：
Infectious Disease Modelling is an open access journal that undergoes peer-review. Its main objective is to facilitate research that combines mathematical modelling, retrieval and analysis of infection disease data, and public health decision support. The journal actively encourages original research that improves this interface, as well as review articles that highlight innovative methodologies relevant to data collection, informatics, and policy making in the field of public health.
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