Safety Assessment of Trialkyl Trimellitates as Used in Cosmetics.

IF 1.2 4区医学 Q4 PHARMACOLOGY & PHARMACY

International Journal of Toxicology Pub Date : 2024-02-01 Epub Date: 2023-12-30 DOI:10.1177/10915818231224248

Monice M Fiume, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler, James G Marks, Ronald C Shank, Thomas J Slaga, Paul W Snyder, Lillian J Gill, Bart Heldreth

引用次数: 0

Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 5 trialkyl trimellitates. These ingredients, which are all structurally related as alkyl esters of trimellitic acid, are reported to function in cosmetics as skin conditioning agents; 2 of the ingredients are also reported to function in cosmetics as plasticizers. The Panel reviewed the available data to determine the safety of these ingredients, and concluded that the trialkyl trimellitates are safe in the current practices of use and concentration when formulated to be non-irritating.

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化妆品中使用的三烷基三甲酸酯的安全评估。

化妆品成分安全专家小组（专家小组）评估了 5 种三烷基偏苯三酸酯的安全性。这些成分在结构上都是偏苯三酸的烷基酯，在化妆品中用作皮肤调理剂；其中两种成分在化妆品中还用作增塑剂。专家小组审查了现有数据，以确定这些成分的安全性，并得出结论认为，三烷基偏苯三酸酯在目前的使用方法和浓度下是安全的，其配方不会产生刺激。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Toxicology 医学-毒理学

CiteScore

3.40

自引率

4.50%

发文量

审稿时长

4.5 months

期刊介绍： The International Journal of Toxicology publishes timely, peer-reviewed papers on current topics important to toxicologists. Six bi-monthly issues cover a wide range of topics, including contemporary issues in toxicology, safety assessments, novel approaches to toxicological testing, mechanisms of toxicity, biomarkers, and risk assessment. The Journal also publishes invited reviews on contemporary topics, and features articles based on symposia. In addition, supplemental issues are routinely published on various special topics, including three supplements devoted to contributions from the Cosmetic Review Expert Panel.