A molecular informatics and in-vitro approach to evaluate the HMG-CoA reductase inhibitory efficacy of monoterpenes, carvacrol and geraniol

IF 2.8 3区综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES

Journal of Taibah University for Science Pub Date : 2023-12-30 DOI:10.1080/16583655.2023.2297456

Sami G. Almalki, Mohammed Alsaweed, Hind Muteb Albadrani, Yaser E. Alqurashi, Mohammed A. Bazuhair, Hamzah H. Ahmed, Parvej Ahmad, Abdulaziz Alfahed, Ayoub Al Othaim, Danish Iqbal

引用次数: 0

Abstract

Currently, statins, the β-hydroxy-β-methyl-glutaryl-CoA reductase (HMG-R) inhibitors, are widely used to lower cholesterol, nevertheless, they have several side effects. Consequently, the present s...

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采用分子信息学和体外方法评估单萜、香芹酚和香叶醇的 HMG-CoA 还原酶抑制功效

目前，他汀类药物，即β-羟基-β-甲基戊二酰-CoA还原酶（HMG-R）抑制剂，被广泛用于降低胆固醇，但它们也有一些副作用。因此，本研究...

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Taibah University for Science MULTIDISCIPLINARY SCIENCES-

CiteScore

6.60

自引率

6.10%

发文量

102

审稿时长

19 weeks

期刊介绍： Journal of Taibah University for Science (JTUSCI) is an international scientific journal for the basic sciences. This journal is produced and published by Taibah University, Madinah, Kingdom of Saudi Arabia. The scope of the journal is to publish peer reviewed research papers, short communications, reviews and comments as well as the scientific conference proceedings in a special issue. The emphasis is on biology, geology, chemistry, environmental control, mathematics and statistics, nanotechnology, physics, and related fields of study. The JTUSCI now quarterly publishes four issues (Jan, Apr, Jul and Oct) per year. Submission to the Journal is based on the understanding that the article has not been previously published in any other form and is not considered for publication elsewhere.