Review finds little benefit from higher-than-recommended doses of stimulants

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Abstract

A systematic review and meta-analysis of studies involving adults with attention-deficit hyperactivity disorder (ADHD) has found small or no benefit from stimulant doses that exceed levels recommended in regulatory guidelines. Unlicensed doses of methylphenidate or amphetamines also were found to increase risk of treatment dropout due to adverse events. Results of the systematic review and meta-analysis were published online Oct. 25, 2023, in JAMA Psychiatry..

研究发现,高于推荐剂量的兴奋剂几乎没有什么益处
一项针对成人注意力缺陷多动障碍(ADHD)患者研究的系统性回顾和荟萃分析发现,兴奋剂剂量超过监管指南建议的水平对患者的益处很小或没有益处。研究还发现,未经许可的哌醋甲酯或苯丙胺剂量会增加因不良反应而放弃治疗的风险。系统回顾和荟萃分析的结果于2023年10月25日在线发表在《美国医学会精神病学杂志》(JAMA Psychiatry)上。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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