Laser Interstitial Thermal Therapy in a Large Thalamic Glioma with Long-Term Remission: A Case Report.

IF 2 4区医学 Q3 ONCOLOGY

Oncology Research and Treatment Pub Date : 2024-01-01 Epub Date: 2023-12-26 DOI:10.1159/000535991

Alexander Hoyningen, Kira-Lee Koster, Marian C Neidert, Oliver Bozinov, Arno Lauber, Olaf Chan-Hi Kim, Thomas Hundsberger, Marie T Krüger

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引用次数: 0

Abstract

Introduction: Thalamic gliomas pose a particular therapeutic challenge as complete resection is rarely achieved due to the deep and eloquent location. Laser interstitial thermal therapy (LITT) may provide a valuable management option for deep-seated gliomas that are not accessible with open surgery.

Case presentation: A 57-year-old woman presented with a rapidly progressive large thalamic glioblastoma. Opting for full ablation, we selected a challenging trajectory to maximize the possibility of full ablation. At 2.4 cm in diameter, the tumour was larger than recommended for LITT; nevertheless, three laser ablations along a single trajectory resulted in macroscopic ablation without complications. Adjuvant radio-chemotherapy was started soon after surgery without radiological recurrence 1.5 years after the initial surgery.

Conclusion: This case demonstrates the potential when thalamic tumours are managed with timely LITT treatment and meticulous trajectory planning. Moreover, it highlights the need for close interdisciplinary management with neurosurgeons, neuropathologists, neuroradiologists, and neurooncologists.

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激光间质热疗治疗大丘脑胶质瘤并获得长期缓解：病例报告。

简介丘脑胶质瘤是一种特殊的治疗难题，因为其位置深且视野清晰，很少能实现完全切除。激光间质热疗（LITT）可为开放性手术无法切除的深部胶质瘤提供有价值的治疗方案：病例介绍：一名 57 岁的女性患有进展迅速的丘脑大胶质母细胞瘤。为了最大限度地实现完全消融，我们选择了一个具有挑战性的手术路径。肿瘤直径为 2.4 厘米，比建议的 LITT 更大；尽管如此，沿单一轨迹进行的三次激光消融术均实现了大面积消融，且未出现并发症。术后很快就开始了辅助放射化疗，在首次手术 1.5 年后未出现放射性复发：本病例展示了丘脑肿瘤通过及时的 LITT 治疗和精心的轨迹规划所具有的潜力。此外，该病例还强调了与神经外科医生、神经病理学家、神经放射学家和神经肿瘤学家进行密切的跨学科管理的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oncology Research and Treatment ONCOLOGY-

CiteScore

3.20

自引率

0.00%

发文量

期刊介绍： With the first issue in 2014, the journal ''Onkologie'' has changed its title to ''Oncology Research and Treatment''. By this change, publisher and editor set the scene for the further development of this interdisciplinary journal. The English title makes it clear that the articles are published in English – a logical step for the journal, which is listed in all relevant international databases. For excellent manuscripts, a ''Fast Track'' was introduced: The review is carried out within 2 weeks; after acceptance the papers are published online within 14 days and immediately released as ''Editor’s Choice'' to provide the authors with maximum visibility of their results. Interesting case reports are published in the section ''Novel Insights from Clinical Practice'' which clearly highlights the scientific advances which the report presents.