Safety and Efficacy of Cervical Ripening and Induction of Labor Using Prostaglandin E1 in Primiparas, Multiparas and Grand Multiparas.

IF 0.7 Q4 OBSTETRICS & GYNECOLOGY

Journal of Obstetrics and Gynecology of India Pub Date : 2023-12-01 Epub Date: 2023-11-15 DOI:10.1007/s13224-023-01847-8

Lior Kashani-Ligumsky, Asaf Bilgory, Ran Neiger

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引用次数: 0

Abstract

Objective: To compare the efficacy and safety of cervical ripening and induction of labor with prostaglandin E1 among primiparas, multiparas and grand multiparas.

Study design: This was a retrospective cohort study.

Results: Between January and December 2017, 1713 women underwent cervical ripening and induction of labor with prostaglandin E1: 523 were primiparas, 656 were multiparas, and 534 were grand multiparas. Four hundred and seventy-nine (91.6%) primiparas delivered vaginally as did 640 (97.6%) multiparas and 521 (97.6%) grand multiparas. Forty-four (8.4%) primiparas underwent cesarean delivery compared to 16 (2.4%) multiparas and 13(2.4%) grand multiparas. Induction to delivery interval was significantly longer in primiparas (29.7 ± 22.8 h). There were no cases of uterine rupture, and the rates of postpartum hemorrhage and endometritis were similar among the three groups. Neonatal outcomes including Apgar score < 7 and umbilical artery pH < 7.1 were not significantly different between the groups.

Conclusion: Using prostaglandin E1 for cervical ripening and labor induction is efficient and safe in primiparas, multiparas and grand multiparas.

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在初产妇、多产妇和大龄多产妇中使用前列腺素 E1 进行宫颈成熟和引产的安全性和有效性。

研究目的比较初产妇、多产妇和巨大多产妇使用前列腺素 E1 进行宫颈成熟和引产的有效性和安全性：这是一项回顾性队列研究：2017年1月至12月期间，1713名妇女接受了宫颈成熟术和前列腺素E1引产：523人为初产妇，656人为多产妇，534人为大多产妇。479名（91.6%）初产妇经阴道分娩，640名（97.6%）多产妇和521名（97.6%）大产妇也经阴道分娩。有 44 名初产妇（8.4%）进行了剖宫产，而多产妇和大产妇分别有 16 名和 13 名（2.4%）进行了剖宫产。初产妇从引产到分娩的间隔时间明显较长（29.7 ± 22.8 小时）。三组产妇均未发生子宫破裂，产后出血和子宫内膜炎的发生率相似。新生儿结局，包括阿普加评分结论：使用前列腺素 E1 进行宫颈成熟和引产对初产妇、多产妇和大产妇都是有效和安全的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Obstetrics and Gynecology of India OBSTETRICS & GYNECOLOGY-

CiteScore

1.30

自引率

0.00%

发文量

124

期刊介绍： Journal of Obstetrics and Gynecology of India (JOGI) is the official journal of the Federation of Obstetrics and Gynecology Societies of India (FOGSI). This is a peer- reviewed journal and features articles pertaining to the field of obstetrics and gynecology. The Journal is published six times a year on a bimonthly basis. Articles contributed by clinicians involved in patient care and research, and basic science researchers are considered. It publishes clinical and basic research of all aspects of obstetrics and gynecology, community obstetrics and family welfare and subspecialty subjects including gynecological endoscopy, infertility, oncology and ultrasonography, provided they have scientific merit and represent an important advance in knowledge. The journal believes in diversity and welcomes and encourages relevant contributions from world over. The types of articles published are: · Original Article· Case Report · Instrumentation and Techniques · Short Commentary · Correspondence (Letter to the Editor) · Pictorial Essay