Global Regulatory and Clinical Overview of Mitochondrial Replacement Techniques in 2023

Abstract

Mitochondrial replacement techniques offer a solution for women at risk of passing on mitochondrial disorders or experiencing infertility. Globally, the regulation of MRT is inconsistent and mostly banned, with the exception of the United Kingdom and Australia in preventing transmission of mitochondrial disorders. The regulatory landscape is constantly changing, and this review aims to explore the status of MRT in select countries as of 2023, including the UK, Australia, the United States, Singapore, Mexico, Ukraine, Greece and Albania.