Optimal treatment strategies in comorbid patients with hypertension and dyslipidemia: the role of fixed-dose combinations

Abstract

The publication reflects the modern strategy and potential of various fixed-dose combinations in comorbid patients with hypertension and lipid metabolism disorders. Based on guidelines and key randomized studies, algorithms for prescribing combination drugs are proposed depending on the clinical characteristics of patients. The priority is both to achieve target blood pressure and low-density lipoprotein levels and to maximize the impact on cardiovascular prognosis and outcomes. Of course, these algorithms are not mandatory, and in a specific clinical situation there may be any deviations even from standard treatment regimens as follows: an alternative decision of a practitioner, intolerance to therapy, special indications, and much more. However, differentiated approach to fixed-dose combinations is extremely useful in cases where it is necessary to quickly make the right decision to prescribe optimal therapy for hypertension and dyslipidemia in lack of time to comprehensively weigh all the pros and cons underlying any clinical guidelines.