Rapid synthesis of Silver Nanoparticles by Rheum ribes L Fruit Peels Anticancer and Antimicrobial Effects with Biocompatible Structures

Abstract

Silver nanoparticles (AgNPs) are useful substances with a wide range of uses. utilizing the extract taken from the peels of the Rheum ribes L.(Rr) fruit growing in the Erzurum region, silver nanoparticles were speedily created in this study utilizing a quick, easy, and environmentally friendly technique without harmful stages. In order to evaluate the attributes of the synthesized Rr-AgNPs, FE-SEM or TEM micrographs were utilized to characterize the morphology of the AgNPs. A UV-visible spectrophotometer was used to assess the highest absorbance bands of RR-AgNPs. These data were used to produce RR-AgNPs, which were characterized as having exclusively negative surface charges of -25 mV, a spherical shape, maximum absorbance at 428 nm wavelength, and 96 nm size distribution. The effectiveness of the produced AgNPs for usage in medical applications was assessed using the MTT technique with microdilution. Minimum Inhibition Concentrations of Rr-AgNPs on pathogen strains were found to range from 0.03-0.50 mg/L. Additionally, it was discovered that AgNPs effectively suppressed malignant cells in the investigation for the anticancer effects of AgNPs, with rates of 86.27%, 74.67%, and 73.49%. Healthy cells were not subjected to any inhibitory effects at the same concentrations that caused this result.