The Effect of Symptoms on the Survival Time of Coronavirus Patients in the Sudanese Population

A. A. Shokeralla, M. E. Qurashi, Reem Yousif Mekki, Mortada S. Ali
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Abstract

The COVID-19 pandemic has rapidly spread worldwide, resulting in substantial rates of illness and death. Gaining insight into the various factors that impact the duration of survival among individuals diagnosed with COVID-19 is of utmost importance to inform clinical practices and public health strategies This study aims to evaluate the relationship between the acuteness of symptoms and the survival time of coronavirus patients in Sudan. The Kaplan-Meier curves and log-rank test were used to determine the symptom pattern. The results of COVID-19 and Cox regression were utilized to determine the most critical symptoms affecting coronavirus patients. The log-rank test revealed that there are differences in the pattern of age and symptoms among coronavirus patients. Cox regression revealed that symptoms affect on the survival time of coronavirus patients. The Cox proportional Hazard Model shows that the hazard of age at any time increases by 116.5%, diarrhea increases by 9%, headache increases by 62.0%, fatigability increases by 13.3%, and other symptoms increase by 47.3%. This study differs from prior studies in several ways. No current study in Sudan has used survival analysis to discover the most relevant symptoms affecting survival time.
症状对苏丹人口中冠状病毒患者存活时间的影响
COVID-19 大流行在全球迅速蔓延,导致大量患者患病和死亡。本研究旨在评估苏丹冠状病毒患者的症状严重程度与存活时间之间的关系。研究采用 Kaplan-Meier 曲线和对数秩检验来确定症状模式。利用 COVID-19 和 Cox 回归的结果来确定影响冠状病毒患者的最关键症状。对数秩检验显示,冠状病毒患者的年龄和症状模式存在差异。Cox 回归显示,症状会影响冠状病毒患者的生存时间。Cox 比例危险度模型显示,任何时间的年龄危险度增加 116.5%,腹泻危险度增加 9%,头痛危险度增加 62.0%,疲劳危险度增加 13.3%,其他症状危险度增加 47.3%。这项研究与之前的研究有几处不同。目前在苏丹进行的任何研究都没有使用生存分析来发现影响生存时间的最相关症状。
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